Bacterial Core Lead Scientist

Job DescriptionJob Description

Title: Bacterial Core Lead Scientist

Location: On site, Frederick, MD

Status: Full Time

Travel: Negligible

Safety Sensitive: No

Salary Range: $80,000-$120,000

Position Summary:

USAMRIID, located at Fort Detrick, Maryland, works closely with other U.S. Army Medical Research and Development Command (USAMRDC) organizations, Department of Defense (DoD), the Interagency (including Interagency Laboratories), and private companies to accomplish its mission of protecting the Warfighter from biological threats and being prepared to investigate disease outbreaks or threats to public health. This includes conducting Research, Development, Testing, & Evaluation (RDTE) of medical countermeasure against biological threats and the safety, quality assurance, project management, and core support required for these research activities.

The Molecular Biology Division works to combat biological threats and weapons of mass destruction by developing high-throughput sequencing and protein profiling to identify emerging pathogens. It also evaluates and improves medical countermeasures, follows the DoD's roadmap for their development, and ensures their ethical use, including FDA approval. The Division also explores expanding indications and combinations with existing countermeasures.

The Bacterial Core Lead Scientist shall serve as Lead Scientist and will conduct basic and applied research on specified bacterial threats, in support of the BD and infectious disease program. The Lead Scientist shall work in BSL-3 laboratories and thus must hold and maintain BPRP status, in accordance with provisions and applicable regulations. This position is contingent upon contract award.

Duties/Responsibilities:

• Plan and perform in vitro minimum inhibition concentration (mic) testing of potential therapeutic compounds against tier 1 bacteria. We currently utilize 30-strain sets of bacillus anthracis (anthrax), yersinia pestis (plague), francisella tularensis (tularemia), burkholderia mallei (glanders), and burkholderia pseudomallei (meliodosis), testing over 72 compounds per year against all 30 strains, in
• Plan and participate in mouse, rat, and rabbit studies, which include preparation of antibiotics for administration, administering drugs and vaccines, orally and by intraperitoneal, intramuscular, subcutaneous, and intravenous administration. In addition, collect animal body fluids and remove tissues with all small-animal studies executed. Upon execution of experiment, this position will perform animal health exams to ensure study remains in compliance with iacuc approved
• Participate in weekly lab meetings and assist in development and design with current and future in vitro and in vivo work. May be requested to present posters at 1 scientific conferences which may require work to be performed outside normal business
• Plan and participate in small-animal bsl-2 pharmacokinetics and toxicology studies; to include preparation of antibiotics for administration; administering drugs and vaccines, followed by blood and tissue collection of pharmacokinetic and pharmacodynamics relationships and efficacy of optimized
• Support the in vivo pharmacology research program and contribute to the multidisciplinary research team to determine pharmacokinetics and pharmacodynamics relationships and efficacy of optimized leads.
• Assist in approximately 4 animal protocols working with bacterial pathogens
• Participate in testing and purifying Anthracis components for efficacy studies.
• Write, plan and execute 1 animal
• Perform approximately 24 elisas per
• Process approximately 150 flow cytometry samples per year
• Test for endotoxin and perform endotoxin remediation when necessary approximately 50 times per
• Purify approximately 16 bacterial products from culture supernatants per year.
• Use computer to analyze data and prepare graphs, do statistics, write lab notes and reports.
• Complete 4 quarterly reports and 1 annual progress reports for dtra per investigator
• Present 2 research findings/presentations at lab meetings and approximately 23 lab meetings per year, and if required, attend approximately 2 scientific meetings or symposia (conus or oconus).
• perform monthly laboratory management to include safety functions and chemical
• Provide 1 scientific support monthly report to tpoc by the last working day of the month. Report will include materials and methods, data and data analysis and should be updated
• Maintain a glp training folder and be compliant with all glp regulations when applicable.

Minimum Requirements:

• Masters Degree in a relevant field, PhD.
• 6 years of experience in bacteriology
• Experience in BSL-2/3 laboratory
• Experience and comfort with animal experiments
• Must be able to obtain/maintain a Secret clearance. Active Secret clearance .
• Must be eligible to enroll in the BPRP and CS-PRP Programs
• Active BPRP and/or CS-PRP status

Work Environment:

• Laboratory environment

Physical Demands:

• May lift up to 25lbs

Benefits:

KIC offers a comprehensive benefits package to eligible full-time employees including: Medical, Dental, and Vision Insurance, 401k with Match, Life and ADD Coverage, Short and Long Term , Paid Time Off and Holidays, Education Assistance/Tuition Reimbursement, Employee Assistance Program, Employee Discount Program, and more!

Apply online at our website: https://kikiktagruk.applicantpool.com/

Disclaimer:

This is not to be an exclusive list of all responsibilities, duties, and skills required of the person in this job. KIC is an Equal Opportunity Employer. KIC considers all applicants for employment without regard to , , , , , , physical or mental , family responsibility, marital status, , political affiliation, veteran's status, , or any other legal protected status.

Please view Equal Employment Opportunity Posters provided by OFCCP here (http://www.dol.gov/ofccp/regs/compliance/posters/ofccpost.htm).

Pursuant to The Alaska Claims Settlement Act 43 U.S.C. Sec. 1601 et seq., and federal contractual requirements, Kikiktagruk Inupiat Corporation, may legally grant certain preference in employment opportunities to KIC Shareholders, and their Descendants.

Successful candidate must pass, comply, and adhere to KIC's Drug and Alcohol policy/testing requirements and may be required to pass a background and/or Motor Vehicle Records check.