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LC-MS Scientist

Job Description

We're hiring for an LC-MS Associate Scientist to join an innovative analytics team driving the development of next- monoclonal antibody therapeutics. If you have experience with LC-MS and a passion for advancing biologics, this could be a great opportunity to apply your skills in a forward-thinking environment.


The Role:


You’ll develop and optimise LC-MS methods (e.g., intact mass and N-released glycosylation analysis) and help establish a robust routine analytical service. Your work will support key characterisation of therapeutic monoclonal antibodies and integrate closely with upstream development teams.


Key Responsibilities:

  • Develop and optimise LC-MS assays for mAb characterisation
  • Set up and maintain a routine LC-MS service, including team training
  • Troubleshoot instrumentation and ensure data quality
  • Standardise analysis templates compatible with ELNs and ML integration
  • Collaborate across scientific teams to ensure alignment
  • Maintain detailed, GLP-compliant experimental records
  • Contribute to SOPs, lab upkeep, and internal presentations


What We're Looking For:

  • BSc or MSc in Biochemistry, Molecular Biology, Analytical Chemistry, or similar
  • 3+ years’ hands-on experience in LC-MS analysis of biologics
  • Strong understanding of assay development and CQA analysis
  • Excellent documentation and problem-solving skills


Bonus Skills:

  • Experience with Waters BioAccord and Benchling
  • Exposure to high-throughput pipelines and broader mAb analytics (e.g., ELISA, qPCR)
  • Familiarity with ICH guidelines and QbD principles


Location: Oxford

Salary: Competitive + benefits


Interested in learning more?

If you have strong LC-MS experience and want to work on impactful biologics projects, we’d love to hear from you. Apply now to explore the next step in your scientific career.

LC-MS Scientist

Oxford, UK
Full time

Published on 04/13/2025

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