Scientist I (Next Generation Sequencing)

Job DescriptionJob Description

To discuss more about this job opportunity, please reach out to Chitrank Rastogi (LinkedIn URL - https://www.linkedin.com/in/chitrank-rastogi-55119a102/), email your updated resume at Email - chitrank.rastogi@collabera.com or give me a call at (425) 523-1648. Thank you!

Job Description:
Job Roles & Responsibilities:

• The Genomics Research Center (GRC) is a center of excellence for genetics and genomics that supports both Discovery and Development.
• The GRC goal is to develop world class genetics and genomics research focused on finding the right therapeutic targets and helping scientists better understand not only human disease biology but also the behavior and response to our drugs in clinical trials across all therapeutic areas.
• The One Functional Genomics team within the GRC provides expertise in genome editing and CRISPR technology to discover and validate novel drug targets for the therapeutic pipelines in Immunology, Oncology and Neuroscience.
• We utilize cutting-edge genomic techniques to transform human genetics data into drug targets and to identify pathogenetic mechanisms.
• We apply high-throughput functional genomic screening approaches to in vitro and in vivo preclinical models with diverse molecular and phenotypic readouts.
• We perform hypothesis-driven research for target validation and execute mechanistic studies utilizing a variety of genomic and non-genomic tools in immortalized cell lines.
• We have an exciting opportunity for a talented and highly motivated scientist to join our collaborative team of geneticists, molecular and cellular biologists, and computational biologists.
• Applicants should have broad laboratory research experience using cell and molecular biology techniques.
• Open communication and curiosity are essential. The candidate is expected to operate in a fast-paced, multi-disciplinary setting and must be able to execute multiple research projects in parallel.

Key Responsibilities:

• Perform CRISPR/Cas9 and CRISPR/Cas12a functional genomics research based on lentiviral and RNP delivery methods
• Participate in cross-functional target identification and validation projects to support early drug discovery efforts in oncology and neuroscience
• Develop cell-based functional assays using cell lines.
• Perform arrayed and pooled CRISPR screens using fluorescent cell sorting
• Perform Molecular Biology techniques such as PCR and NGS library generation.
• Collaborate extensively with scientists across diverse functional and therapeutic areas in a matrixed research environment
• Communicate and present project designs and results clearly, both to individual stakeholders and in group settings

Qualifications:

• Bachelors or Masters in Molecular biology, Cell biology, or in a related discipline with expertise in immortalized cells.
• Experience in molecular biology techniques, such as PCR and NGS library synthesis, is required
• Experience in in vitro cell culture and development of cell-based assays is required.
• Experience in transfection, nucleofection, and lentiviral transduction is highly desirable.
• Ability to learn new skills and apply them in a fast-paced research environment is a must
• Creativity, problem-solving, and attention to details are required
• Strong communication and collaboration skills are essential. Ability to work independently as well as in a team is a must.

Company DescriptionCollabera is a Global Digital Solutions Company providing Software Engineering Solutions for the world's most tech-forward organizations in the areas of Engineering, Cloud and Data/AI. With its roots serving the engineering needs of the world's most recognized businesses in Technology, Financial Services, Telecom and Healthcare, Collabera today operates across 60 locations in 11 countries, serves 30% of the Fortune 500, and has exceeded the industry growth rate by 3-4x for several years.Company DescriptionCollabera is a Global Digital Solutions Company providing Software Engineering Solutions for the world's most tech-forward organizations in the areas of Engineering, Cloud and Data/AI. With its roots serving the engineering needs of the world's most recognized businesses in Technology, Financial Services, Telecom and Healthcare, Collabera today operates across 60 locations in 11 countries, serves 30% of the Fortune 500, and has exceeded the industry growth rate by 3-4x for several years.]]>